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2024 Translational Science Ensemble Awards

2024 Translational Science Ensemble Awards

The Clinical & Translational Science Institute of Southeast Wisconsin (CTSI) will advance the field of translational science by funding two Translational Science Research Ensembles, $50,000 each. The product of these Ensembles should result in the identification and removal of obstacles and roadblocks that slow the performance and progress of Translational Research.

Letter of Intent deadline was November 27th, 2023. Letter of Intent submission is now closed.

Translational research, as we are familiar with, is defined as the endeavor to traverse steps of the translational process for a particular target or disease. Whereas translational science is defined as the field of investigation focused on understanding the scientific and operational principles underlying each step of the translational process. The discovery of the scientific, mechanistic, and operational principles of the intervention development and dissemination process, provides the scientific foundation for improving translational efficiency and accelerating interventions that improve health.


Translational Science: “Sometimes the System or Process is Sick”

For this award, Translational Science Research Ensembles will not conduct clinical and translational research to address an unmet patient medical need. Instead, funded Ensembles will focus their research activities and expertise exclusively on understanding the scientific and operational principles underlying a specific step(s) of a translational process, with the goal to improve translational efficiency. Teams will form around an identified translational barrier of their choice, and create solutions that accelerate the translational process. Because this award does not require focusing on a specific disease, the results of this research have the potential for broad impact that can benefit a greater number of patients, without regard to the specific disease or condition.

Ensemble teams may address any underlying Translational Science barriers.

Examples of Research Targets:  

  • Impediments that prevent:
    • translation of basic science discoveries into first-in-human investigation
    • collaboration between basic scientists and clinician scientists
    • meaningful participation and collaboration of community members in the research process
    • patient data de-identification
    • clinic uptake/adoption of new process
    • phase-out of outdated clinical processes
  • Connecting parallel research activities/strategies to increase efficiency and innovation
  • Increasing inpatient clinical trial recruitment
  • Implementing efficiencies for recruitment, e.g., automatic opt-in, or E-consent process
  • Standardizing education and training for clinical research
  • Accelerating the patent or commercialization process
603 KBView the full 2024 Translational Science Ensemble Award RFA


Important Dates

  • October 11, 2023 – RFA Release
  • October 16, 2023 – Begin Consultation Sessions
  • October 31, 2023: – Town Hall RFA Discussion (Virtual) at Noon.* View the Recording (Passcode: n2S21$h0)
  • November 1, 2023: – Town Hall RFA Discussion (Virtual) at 5pm.*
  • November 27, 2023: – Letter of Intent (Required) – Letter of Intent submission is now closed.
  • By December 15, 2023: – Begin Pre-Ensemble meetings (Required) with CTSI Project Manager and applicant team for team building, development of shared goals, and proposal development.
  • March 11, 2024 – Proposal Deadline; Allows ~5 months for Pre-Ensemble meetings and proposal development
  • April 8, 2024 – Start Date

*Video recording for those that cannot attend

HIGHLY RECOMMENDED: Schedule a consultation session to review ideas and ask questions. Contact Mike Anello (manello@mcw.edu).

Questions: Please contact Mike Anello (manello@mcw.edu) or David Zimmerman (dzimermman@mcw.edu).

NIH Funding Acknowledgment: Important Reminder – Please acknowledge the NIH when publishing papers, patents, projects, and presentations resulting from the use of CTSI resources by including the NIH Funding Acknowledgement.


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