Letter of Intent deadline was December 11th, 2023. LOI submission is now closed.
Translational research, as we are familiar with, is defined as the endeavor to traverse steps of the translational process for a particular target or disease. Whereas translational science is defined as the field of investigation focused on understanding the scientific and operational principles underlying each step of the translational process. The discovery of the scientific, mechanistic, and operational principles of the intervention development and dissemination process, provides the scientific foundation for improving translational efficiency and accelerating interventions that improve health.
Translational Science: “Sometimes the System or Process is Sick”
Examples of translational science research targets:
- Impediments that prevent:
- translation of basic science discoveries into first-in-human investigation
- collaboration between basic scientists and clinician scientists
- meaningful participation and collaboration of community members in the research process
- patient data de-identification
- clinic uptake/adoption of new process
- phase-out of outdated clinical processes
- Implementation of novel research methods such as decentralized trials, platform trials or n-of-1 trials
- Connecting parallel research activities/strategies to increase efficiency and innovation
- Increasing inpatient clinical trial recruitment
- Implementing efficiencies for patient recruitment, e.g., automatic opt-in, or E-consent process
- Standardizing education and training for clinical research
- Accelerating the patent or commercialization process
Team Members
The Translational Research AND Translational Science Research Ensemble will integrate various experts and stakeholders to address a specific unmet patient medical need(s) and translational science barrier(s). The composition of a CTSI Ensemble is multidisciplinary, and may include basic, clinical, translational, and community health investigators, as well as clinicians, patient representatives, advocacy groups, community stakeholders, and health system experts.
Important: The addition of patients and community members adds critical perspectives that help guide the team’s direction. Members of the team can also provide context-driven feedback after the Ensemble completes a research project.
Eligibility
All investigators and translational research accelerators at CTSI partner institutions are eligible to participate in this funding opportunity. Partner institutions include Medical College of Wisconsin, University of Wisconsin-Milwaukee, Marquette University, Milwaukee School of Engineering, Children’s Wisconsin, Versiti Blood Center, Froedtert Hospital, and Zablocki Veterans Affairs Medical Center.
Important Dates
- October 30, 2023 – RFA Release
- November 6, 2023 – Begin Consultation Sessions
- November 14, 2023: – Town Hall RFA Discussion (Virtual) at Noon.* View the Recording (Passcode: bB?ee+61)
- November 15, 2023: – Town Hall RFA Discussion (Virtual) at 5pm.*
- December 11, 2023: – Letter of Intent (Required)
- By January 12, 2024: – Begin Pre-Ensemble meetings (Required) with CTSI Project Manager and applicant team for team building, development of shared goals, and proposal development.
- March 25, 2024 – Proposal Deadline; Allows ~5 months for Pre-Ensemble meetings and proposal development
- April 22, 2024 – Start Date
*Video recording for those that cannot attend
656 KBView the full Request for Applications
Please contact David Zimmerman (dzimmerman@mcw.edu) with any questions.
