Multi Center Trials

Multi Center Trials

The Trial Innovation Network is a collaborative initiative within the CTSA Program and is composed of three key organizational partners – the CTSA Program Hubs, the Trial Innovation Centers (TICs), and the Recruitment Innovation Center (RIC).

The vision for the Trial Innovation Network is to innovatively address critical roadblocks in clinical trials and accelerate the translation of novel interventions into life-saving therapies. The Trial Innovation Network is a collaborative national network that focuses on operational innovation, operational excellence and collaboration and will leverage the expertise and resources of the CTSA Program. The Trial Innovation Network will feature a single IRB system, master contracting agreements, quality by design approaches, and a focus on evidence-based strategies to recruitment and patient engagement.

The goal of the Trial Innovation Network is to not only execute trials better, faster, and more cost-efficiently but, importantly, to be a national laboratory to study, understand and innovate the process of conducting clinical trials.

The investigators are currently building the key elements of the Trial Innovation Network. The goal is to start early projects as soon as possible and collaborate with other NIH Institutes and partners to launch clinical trials in 2017.

For a description of the organization and key elements of the Trial Innovation Network, please see the Who We Are page.

The CTSI, in collaboration with five other CTSA sites in the Midwest (University of Wisconsin-Madison, Mayo Clinic, University of Minnesota, Indiana State University and Ohio State University), has formed a consortium – MARCH (Midwest Area Research Consortium for Health) to enable the most cost effective and efficient conduct of a multisite clinical trial at one or all of these Universities.

The aim of MARCH is to conduct trials under one IRB submission one contract for all sites. The CTO acts as a gateway to MARCH services for CTSI investigators.

NIH Funding Acknowledgment: Important Reminder – Please acknowledge the NIH when publishing papers, patents, projects, and presentations resulting from the use of CTSI resources by including the NIH Funding Acknowledgement.


Children's Hospital of WisconsinMarquette UniversityMSOEUWMVersitiVA Medical Center