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PCORI Funding Opportunities

Explore Upcoming PCORI Funding Opportunities

To advance its mission to help people make better-informed healthcare decisions, the Patient-Centered Outcomes Research Institute (PCORI) offers funding opportunities for high-quality patient-centered comparative clinical effectiveness research (CER) and related projects through PCORI Funding Announcements (PFAs). Several new PCORI Funding Announcements (PFAs) will open Aug. 12 and PCORI will be hosting virtual applicant town halls for prospective applicants to learn more about the PFAs under Cycle 3 2025. 

Dates and Times for Virtual Applicant Town Halls

  • Broad Pragmatic Studies
    • Monday, Aug. 18, 2025, 11:30 am - 1 pm (ET)
  • Addressing Rare Diseases
    • Tuesday, Aug. 19, 2025, noon - 1 pm (ET)
  • Phased Large Awards for Comparative Effectiveness Research
    • Wednesday, Aug. 20, 2025, 11:30 am - 1 pm (ET)
  • Advancing the Science of Engagement in Research
    • Friday, Aug. 22, 2025, noon - 1 pm (ET)

Attendees will hear from PCORI staff about the PFAs and gain insights on submitting responsive Letters of Intent and applications for high-quality patient-centered comparative clinical effectiveness research and related projects. Letters of Intent for the funding opportunities will be due Sept. 23 by 5 pm (ET).

To register for an upcoming Town Hall session, visit: https://www.pcori.org/funding-announcement-notice/2025/virtual-applicant-town-halls-upcoming-funding-opportunities-register-now

To review all open and upcoming funding opportunities, visit: https://www.pcori.org/funding-opportunities.

The Clinical and Translation Science Institute’s (CTSI) Center for Biomedical Informatics (CBMI) is a member of the GPC (Greater Plains Collaborative), a clinical research network within PCORnet®, the Patient-Centered Clinical Research Network. CBMI welcomes and facilitates collaboration across GPC sites and PCORnet® networks. PCORnet® is a national resource, funded by PCORI, where high quality health data, patient partnership, and research expertise deliver fast, trustworthy answers that advance health outcomes. Interested researchers can reach out to CBMI at cbmi-ri@mcw.edu to learn more about PCORnet®.