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PCORI Funding Opportunities

Explore Upcoming PCORI Funding Opportunities

Several new research Patient-Centered Outcomes Research Institute (PCORI) Funding Announcements (PFAs) will open Dec. 2 and PCORI is hosting virtual applicant town halls for prospective applicants to learn more about these PFAs.

Attendees will hear from PCORI staff about the PFAs and gain insights on submitting responsive Letters of Intent (LOIs) and applications for high-quality patient-centered comparative clinical effectiveness research (CER) studies and related projects. LOIs for these PFAs are due Jan. 6, 2026, by 5 pm (ET).

PCORI funds patient-centered comparative clinical effectiveness research (CER) that generates evidence to help patients, caregivers and the broader healthcare community make informed healthcare decisions. If your research aligns with PCORI’s mission, consider attending an Applicant Town Hall. These sessions provide an opportunity to connect with staff, ask questions and refine your LOI. 

To register for an upcoming Town Hall session, visit the PCORI Registration page.

Review all open and upcoming funding opportunities, visit the PCORI Funding Opportunities web page.

The Clinical and Translation Science Institute’s (CTSI) Center for Biomedical Informatics (CBMI) is a member of the GPC (Greater Plains Collaborative), a clinical research network within PCORnet®, the Patient-Centered Clinical Research Network. CBMI welcomes and facilitates collaboration across GPC sites and PCORnet® networks. PCORnet® is a national resource, funded by PCORI, where high quality health data, patient partnership, and research expertise deliver fast, trustworthy answers that advance health outcomes. Interested researchers can reach out to CBMI at cbmi-ri@mcw.edu to learn more about PCORnet®.