• CTSA-funded sites known for cutting edge, performance driven research
  • Access to multidisciplinary investigators and study teams
  • Good Clinical Practice (GCP)-trained personnel at each performance site
  • Established Standard Operating Procedures for quality assurance
  • Consistent and effective communication among MARCH leadership and study teams
  • Mission consistent with national research goals of regionalization and collaboration
  • All sites are accredited by the Association for the Accreditation of Human Research Protections Program (AAHRPP)


  • Implement multisite research protocols more quickly and cost-effectively
  • Effective administration and coordination mechanisms through a centralized model
  • Dedicated leadership and study personnel at each site to enhance communication, continuity, and to assist with coordination
  • Standardized data management across sites via clinical trial management system software
  • Streamlined regulatory approval process providing a single Institutional Review Board (IRB) of record
  • Simplified fiscal management: one contract, one budget, one contact
  • Access to larger, more diverse populations leading to increased generalizability

Geographic Reach & Diversity

  • Recruitment across multiple Midwest sites optimizing accrual success, particularly in studies of rare disease states or those that require an inordinately large sample size
  • Geographic reach of ethnic and socioeconomic representation across the  Midwest enabling study of the differences in the causes, occurrence, and characteristics of diseases across populations
  • Collective power of large and diverse subject populations from academic institutions across multiple states facilitating rapid enrollment
  • Access to greater than 22 million residents across member sites

Professional Development & Relationship Building

  • Obtain skills related to interdisciplinary, team-based science
  • Build relationships and organizational alliances