Integrating Research into Clinical Practice (IRCP): Innovations in Healthcare Delivery Initiative

Integrating Research into Clinical Practice (IRCP): Innovations in Healthcare Delivery Initiative

The Integrating Research into Clinical Practice (IRCP): Innovations in Healthcare Delivery Pilot Grants are supported by the Medical College Physicians Group (MCP) and the Clinical and Translational Science Institute of Southeast Wisconsin (CTSI). The fundamental goal of this RFA is to stimulate innovative pilot projects that promise to measurably and meaningfully improve delivery of healthcare in terms of clinical quality, patient experience, value and efficiency through development of Research Product Lines (RPLs).


Open for applications

MCW Grants & Contracts Submission Deadline: July 22, 2016

CTSI Application Submission Deadline: July 29, 2016

Innovations in Healthcare Delivery: Integrating Research into the Clinical Practice Initiative
Integrating Research into the Clinical Practice research focuses on discovery and the application of scientific findings into a real-world setting to improve quality of care. It is the goal of the MCP and CTSI to encourage novel approaches to solving complex health related problems and improve health outcomes by creating new, bidirectional flows of information for efficient and effective delivery of healthcare.

2016 Integrating Research into Clinical Practice (IRCP): Innovations in Healthcare Delivery Pilot Grants RFA
Key Dates

Key Dates

  • MCW Grants & Contracts Submission Deadline: July 22, 2016, 11:59am CDT
  • CTSI Application Submission Deadline: July 29, 2016, 11:59pm CDT
  • Review Process: August/September 2016
  • Decision Letters Sent: September 15, 2016
  • Funds Available for Awarded Projects: October 15, 2016



This grant is intended to fund the formation of RPLs to solve important clinical problems. Therefore, the applications will be reviewed with a focus on:

  • Research Product, i.e., the clinical issue being resolved, the impact of solving this problem and the feasibility of achieving this goal.
  • Members of the Research Product Line, i.e., qualified investigators working on the research question,
  • Qualifications of the Research Product Line Leader (i.e., Principal investigator) to deploy the team’s expertise and the ability of the team to operate effectively.


Research Product is defined as the outcome of investigation into a clinical problem. This outcome may include improved process, facilitated access, improved patient satisfaction, new diagnostic or therapeutic modalities; cheaper, faster and better diagnostic or treatment outcomes.

Research Product Line is defined as a team of investigators comprised of clinicians and members of a research team with relevant complementary disciplines aiming to develop a well-defined research product. This team is envisioned to be inter- or trans-disciplinary and include those with the expertise necessary to deliver the research product. MCP and CTSI seek to encourage applicants to take advantage of available expertise in the continuum of care and related disciplines such as: nursing, social scientists, ethicists, biostatisticians, informatics specialists, human factors specialists, industrial engineers and other members of clinical care delivery teams in developing the Research Product Line.

Research Product Lines are anticipated to incorporate the following principles in their operations: Collaboration, Transformation, Facilitation and Education. CTSI will provide a research counselor to each awarded product line to support the team with intellectual and research advice.

CTSI Support

  • All Applicants, whether funded or not, have the ability to receive assistance and support with grant writing, IRB pre-review, and IRB navigation from CTSI.
  • CTSI can assist with identifying potential interdisciplinary and inter-institutional collaborators for projects. Investigators that are interested in forming new collaborative relationships are encouraged to contact CTSI. We will assist you with identifying potential interdisciplinary and inter-institutional collaborators for these projects.

Does your project include working with federal agencies or include pharmacological and/or material transfer agreements?
If so, please contact CTSI Pilot Translational and Clinical Studies Program Director, Ramona Tenorio, PhD at 414-955-2537, prior to applying.



General Guidelines and Eligibility

  • Projects will be funded at a level up to $25,000. Institutional and departmental cost sharing to supplement these funds is highly encouraged.
  • The Research Product Line Leader must be a Medical College Physicians Group (MCP) or Froedtert Health & Medical College of Wisconsin Community Physicians (CP) member and an affiliate of the CTSI Healthcare System Partnership.
  • The Research Product Line Leader’s principal clinical practice is under the auspices of MCP or CP.
  • The project setting must be in either MCP or CP affiliated practices.
  • The project’s duration will be 12 months or less.
  • All Research Product Line investigators and personnel must be clearly identified in the proposal.
  • All Research Product Line investigators must be CTSI Members. To become a member, please complete the CTSI Membership Form.
  • Investigators are encouraged to submit regulatory applications (IRB/IACUC, etc.) at time of application. If applicable, proof of any Exempt Status must be provided.
  • Applicants are encouraged to contact CTSI IRB Navigator, Sonia MaldonadoSchmidt: and MCW IRB Coordinator, Connie Byrne: at the time of application for assistance in managing IRB(s).
  • Research Product Line Leader will be expected to comply with reporting, presentation and meeting requirements as a condition of receipt of funds.
  • Letter(s) of Support for project from PI(s) Department Chair(s) and/or Clinical Supervisor(s) is required.

Review Process

Review Criteria

The Clinical and Translational Science Institute will convene a special review panel comprised of members with expertise in clinical science to manage the review process and assign reviewers. Each application will be reviewed by a minimum of 2 reviewers.

Funds will be provided to proposals with strengths in the following areas:

  • Proposals with potential for broad, sustainable clinical impact
  • Proposals that creatively improve practice(s) and decrease costs
  • Proposals that are simple, discreet, and conclude within one year

All Integrating Research into the Clinical Practice pilot grant applications will be reviewed; grants awarded will depend solely on the quality of the applications. Pilot projects are intended to lead to tangible clinical improvements.

Specific Review Criteria

Overall Impact/Priority Score
Reviewers will provide an overall impact/priority score to reflect their assessment of the likelihood for the project to lead to an improved delivery of healthcare through the development of a Research Product Line (RPL). Consideration of the following program specific review criteria should be given:

1. Significance

  • What is the likelihood that the objectives outlined in the proposal will be achieved?
  • If the aims of the project are achieved, how will clinical practice be improved?
  • How will successful completion of the aims change the concepts, methods, technologies, treatments, services or preventative interventions that drive this field?

2. Investigator(s)

  • Are the PD/PIs, collaborators and other researchers well suited to the project?
  • Do the investigators have complementary and integrated expertise; is their leadership approach, governance and organizational structure appropriate for the project?

3. Innovation

  • Does the application challenge and seek to shift current clinical practice paradigms by utilizing a refinement, improvement or new application of theoretical concepts, approaches or methodologies, instrumentation, or interventions?

4. Approach

  • Are the overall strategies, methodologies, and analyses well-reasoned and appropriate for developing the research product as proposed?
  • Is the approach thoughtfully conceived and carefully planned?
  • Are potential problems, alternative strategies, and benchmarks for success presented?
  • If the project is in the early stages of development, will the strategy establish feasibility, and will particularly risky aspects be managed?

5. Environment

  • Will the clinical environment in which the work will be done contribute to the probability of success?
  • Are the institutional support, equipment and other physical resources available to the investigators adequate for the project proposed?
  • Will the project benefit from unique features of the clinical environment, patient populations, or collaborative arrangements?

6. Feasibility

  • Is the pilot project a discrete, well defined project that realistically can be completed in one year or less and requires limited levels of funding to obtain pilot data?
  • If the project requires complex regulatory approvals or agreements (examples include: complex IRB submissions, NIDA, FDA, including IND and IDE applications) or pharmacological agreements (e.g. clinical trial agreements, material transfer agreements), is there a well stated plan that would make it possible for the project to receive approvals and participate in a timely manner?

How to Apply

Submission Details

The online IRCP Application Form must be completed and received by July 29, 2016, 11:59pm CDT. Submissions by any other means will not be accepted.

Elements & Requirements of the Application

  • 2016 Integrating Research into Clinical Practice Application Form
  • Budget and Budget Justification Form (1 per partnering institution/agency)
  • NIH Biographical Sketch (all PIs and all Co-Investigators; limit 5 pages per individual)
  • Letter(s) of Support for project from PI(s) Department Chair or Clinical Supervisor
  • Letters of Support from each Co-Investigator to the PI(s)
  • MCW Faculty Cost Sharing Commitment Form (if applicable)

Additional Information

These awards need to be processed through MCW Grants and Contracts using the non-eBridge Registration Form and MCP identified as the funding source. Please contact MCW Grants and Contracts for more information or assistance with this process,

NIH Funding Acknowledgment: Important Reminder – Please acknowledge the NIH when publishing papers, patents, projects, and presentations resulting from the use of CTSI resources by including the NIH Funding Acknowledgement.

Zablocki VA Medical CenterFroedtert HospitalMedical College of Wisconsin Childrens Hospital of WisconsinBloodCenter of WisconsinUniversity of Wisconsin - MilwaukeeMarquette UniversityMilwaukee School of Engineering