Translational Cardiac & Vascular Function Unit

Translational Cardiac & Vascular Function Unit

The Translational Cardiac and Vascular Function Unit, situated in the Adult TRU, has been folded into the TRUs for CTSI investigator use.

Technology & Resources

  • GE Vivid 7 echocardiograph and 3S probe are available for human cardiac echocardiography
  • Data analyzed using GE Q analysis software (EchoPAC platform)
  • Three separate vascular ultrasound units (GE Logiq 500, Sonosite 180 plus, and a newer all digital Sonosite MicroMaxx unit, each with probes for high resolution vascular or cardiac imaging) are coupled with Brachial Analysis software for quantifying flow-induced vasodilation and with software for calculating intimal medial thickness and available exclusively for research
  • Separate Itamar EndoPat 2000 tonometry unit for non-invasive assessment of endothelial function is dedicated for use by CTSI investigators, a SphygmoCor® Px Pulse Wave Velocity System, and a SphygmoCor® Mx Pulse Wave Velocity System for non-invasive, reproducible measures of arterial stiffness has recently been acquired.
  • Hokanson Digital Venous Plethysmograph.

TRU Terms & Attestations

TRU Terms & Attestations

Terms

  • The TRU requires a fully signed Letter of Agreement (LOA), a study roll-out meeting, and a copy of the Institutional Review Board (IRB) Approval letter before the study may begin.
  • Cancellation of Requested Services: Please provide notice of at least 48 hours for cancellation of requested services.
  • Scheduling of Requested Services: Please email tru_scheduling@ chw.org to set up a study appointment. Availability is to the best of our ability with variables including but not limited to: already scheduled services for this or any other study, availability of appropriate staff, and availability of appropriate physical space.
  • The TRU fees are subject to change. Every effort will be made to minimize the amount and frequency of such changes.
  • As a practice, the TRU will maintain study documentation in EPIC. It is up to the individual study team to create and maintain their own source documents per their study requriements. Notify TRU RNs if certain elements need to be added to the EPIC progress note (i.e. vial number or kit lot numbers). If any additional documents outside of EPIC are kept in the PTRU, they will be turned over to the Principal Investigator at the time of study completion in the PTRU.
  • As a CTSI Investigator, you agree to participate in the TRU’s annual satisfaction survey process.
  • Should additional services be requested, a new proposal may be created to outline the scope of the request and associated cost-sharing fees. This LOA will be amended as necessary.
  • If any changes are made in your protocol, it is the study team’s responsibility to provide any updated IRB approved forms and review any procedural changes with the PTRU Nurse Manager prior to the next participant’s scheduled visit.
  • The TRU will bill on a monthly basis for all services rendered.
  • Payment for services performed will be expected upon receipt of a billing statement.

Attestations

  • On behalf of the department/division/institute or other professional jurisdiction that you represent, you attest that all of the following conditions have been satisfied:
    • The Principal Investigator is a faculty member, credentialed physician, licensed nurse or licensed pharmacist (as applicable) in good standing;
    • The Principal Investigator is approved to devote the proposed time and effort to this project;
    • If the Principal Investigator’s application identifies Department/Division/Institute funds to support this project, this Department/Division/Institute endorses this commitment;
    • The project has scientific merit, uses procedures consistent with sound research design, and is likely to yield the expected knowledge; and
    • The proposal is a complete and coherent one.
  • You agree to cite the Pediatric TRU of Children’s Hospital of Wisconsin on all publications arising from any research project receiving support from the PTRU.
  • If you are funded by a CTSI award, you agree to cite CTSA NIH Grant UL1TR001436 and if applicable KL2TR001438 on all publications arising from any research project receiving support from the CTSI. Publications arising from any research project receiving support from the CTSI must acknowledge such support by stating the following:
    • “Support received by grant UL1TR001436 from the Clinical and Translational Science Award (CTSA) program of the National Center for Advancing Translational Sciences.”
    • KL2 Scholars: “Support received by grants UL1TR001436 and KL2TR001438 from the Clinical and Translational Science Award (CTSA) program of the National Center for Advancing Translational Sciences.”

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Contact Us

Contact Us

Michael Widlansky, MD, Director 
414-955-6716

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NIH Funding Acknowledgment: Important Reminder – Please acknowledge the NIH when publishing papers, patents, projects, and presentations resulting from the use of CTSI resources by including the NIH Funding Acknowledgement.

PARTNERS

Zablocki VA Medical CenterMedical College of WisconsinMSOE