The CTSI Biomedical Informatics Service represents the centralized IT systems, data management and analysis resources for CTSI staff and investigators. This is accomplished through the provisioning of equipment, software, and assistance with establishing and maintaining databases.
The primary functions of the CTSI Biomedical Informatics service are as follows:
This is accomplished by balancing ease of use while also providing security of all electronic patient data. Requests for Biomedical Informatics support are reviewed by the CTSI Research Review Committee at the time of protocol submission. Once a protocol has been approved by the Research Review Committee and the IRB we meet with the investigator to determine data collection and management tools best suited for the project.
The following factors are used to determine these tools:
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i2b2 (Informatics for Integrating Biology and the Bedside) is an NIH-funded National Center for Biomedical Computing based at Partners HealthCare System. The i2b2 Center is developing a scalable informatics framework that will enable clinical researchers to use existing clinical data for discovery research and, when combined with IRB-approved genomic data, facilitate the design of targeted therapies for individual patients with diseases having genetic origins. This platform currently enjoys wide international adoption by the CTSA network, academic health centers, and industry. i2b2 is funded as a cooperative agreement with the National Institutes of Health.
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Biomedical Informatics assists in the configuration of systems for data acquisition for numerous CTSI protocols. This involves working with the principal investigator, study staff and when necessary the instrument manufacturer, to connect to CTSI computers and securely transfer data for backup and storage.
Biomedical Informatics works with the investigator to determine the best data entry/storage application to use for the given study.
REDCap
We provide management and support for REDCap (Research Electronic Data Capture), developed through a collaboration project with Vanderbilt University and 20 other GCRC/CTSA sites.
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